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Safety Considerations in Recombinant DNA Research with Pathogenic Viruses

NIH Recombinant DNA Advisory Committee Meeting

September 21, 2004

Bethesda Marriott
Bethesda, Maryland


Videos

Morning Session before break (2 hrs 45 mins - Real Video)

Morning Session after break (42 mins- Real Video)

Afternoon Session before break (1 hr 50 mins - Real Video)

Afternoon Session after break (1 hr 10 mins - Real Video)

Caption Text

AGENDA


8:30 a.m. - 8:40 a.m. Opening Remarks
Elias Zerhouni, M.D., Director, NIH

Opening Remarks (Real Video)

Dr Zerhouni's Introductory - RAC Safety Symposium - Presentation (PDF)

8:40 a.m. - 9:00 a.m. Welcome and Introduction
Moderators: Neal DeLuca, Ph.D., University of Pittsburgh - Presentation (PDF)
Kathryn Holmes, Ph.D., University of Colorado - Presentation (PDF)

Welcome and Introduction (Real Video)

9:00 a.m. - 9:15 a.m. Roundtable Introductions

Roundtable Introductions (Real Video)

Session I: Recombinant Influenza Virus Research

9:15 a.m. - 9:45 a.m. Reverse Genetics Techniques to Generate Recombinant Viruses
Yoshihiro Kawaoka, D.V.M., Ph.D., University of Wisconsin, Madison

Recombinant Influenza Virus Research (Real Video)

Reverse Genetics Techniques to Generate Recombinant Viruses (PDF)

9:45 a.m. - 10:15 a.m.Characterization of the 1918 Influenza Virus
Adolfo García-Sastre, Ph.D., Mount Sinai School of Medicine

Characterization of the 1918 Influenza Virus (Real Video)

Characterization of the 1918 Influenza Virus (PDF)

10:15 a.m. - 10:45 a.m. Highly Pathogenic Avian Influenza Virus Research
Robert Webster, Ph.D., St. Jude Children's Research Hospital

Highly Pathogenic Avian Influenza Virus Research (Real Video)

Highly Pathogenic Avian Influenza Virus Research (PDF)

10:45 a.m. - 11:15 a.m. Vaccine Applications
Kanta Subbarao, M.D., M.P.H., National Institute of Allergy and Infectious Diseases, NIH

Vaccine Applications (Real Video)

Vaccine Applications (PDF)

11:15 a.m. - 11:30 a.m. Break

Session II: SARS - Corona Virus

11:30 a.m. - 12:00 noon Recombinant SARS-CoV Research
Ralph Baric, Ph.D., University of North Carolina, Chapel Hill

Recombinant SARS-CoV Research (Real Video)

Recombinant SARS-CoV Research (PDF)

12:00 noon - 1:00 p.m. Lunch

Session III: Lessons from Research with Infectious Viruses

1:00 p.m. - 1:15 p.m. Early Research with HIV
Larry Arthur, Ph.D., National Cancer Institute at Frederick, NIH

Early Research with HIV (Real Video)

Early Research with HIV (PDF)

1:15 p.m. - 1:30 p.m. Newcastle Disease Virus Research
Siba Samal, Ph.D., M.V.Sc., University of Maryland, College Park

Newcastle Disease Virus Research (Real Video)

Newcastle Disease Virus (PDF)

Session IV: Guidance Provided by the NIH Guidelines for Research Involving Recombinant DNA Molecules and Biosafety in Microbiological and Biomedical Laboratories (4th edition) and U.S. Department of Agriculture (USDA) Regulations

1:30 p.m. - 2:00 p.m. Risk Assessment and Containment
Emmett Barkley, Ph.D., Howard Hughes Medical Institute

Risk Assessment and Containment (Real Video)

Risk Assessment and Containment (PDF)

2:00 p.m. - 2:15 p.m. Update on the Revision to the Influenza Section of Biosafety in Microbiological and Biomedical Laboratories (4th edition)
Deborah Wilson, Dr.P.H., CBSP, Office of Research Services, NIH

Update on the Revision to the Influenza (Real Video)

Impact on Influenza Research in the United States (PDF)

2:15 p.m. - 2:30 p.m. USDA Guidance
Lee Ann Thomas, D.V.M., M.S., Animal and Plant Health Inspection Service, USDA

USDA Guidance (Real Video)

2:30 p.m. - 3:00 p.m. Public Questions and Comments

3:00 p.m. - 3:15 p.m. Break

3:15 p.m. - 5:00 p.m.
Discussion of Points to Consider to Assist Institutional Biosafety Committee Reviews

Discussion of Points to Concider (Real Video)

5:00 p.m. Adjournment

 

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